Sesebelisoa sa python se bonolo, se behiloeng-le-ho lebala bakeng sa ho fetoha lipakeng tsa lihlooho tsa desktop ho latela lihora tse bobebe le tse lefifi. Hona joale, libaka tsena tsa li-desktop li tšehetsoa ka tlhaho: GNOME le tse ling tsa GNOME tse thehiloeng kapa tse tšoanang tse kang Unity, KDE Plasma, XFCE le Cinnamon. Ho phaella moo, hore na DE ea hau e thathamisitsoe ka holimo kapa che, u ka boela ua iketsetsa le ho eketsa mangolo a hau.